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As shown in Figure 2, as the rate-limiting step in the synthesis of fatty acids, acetyl-CoA reacts with bicarbonate and ATP to form malonyl-CoA, which is catalyzed by acetyl-CoA carboxylase (ACC/POD-2)

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Phosphate starvation in fungi induces the replacement of phosphatidylcholine with the phosphorus-free betaine lipid diacylglyceryl-N, N N-Trimethylhomoserine

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