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doi: 10.5492/wjccm.v6.i1.85

L-Carnitine L-Carnitine is an amino acid derivative involved in fat metabolism

The mechanisms by which PPAR loss leads to aberrant apoptosis and reduced cell survival have been associated to altered lipid metabolism and accumulation of stress and pro-inflammatory molecules such as reactive lipids and ROS deriving from the 5-LO and COX2 pathways, that specifically activate a lipid-mediated programmed cell death [33]

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