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Discontinue use if hypersensitivity or allergy occurs

Sonia SB, Siddiki MN, Sultana S, Chowdhury IH, Sinha S, Ahmad R, et al

O-L, low expression of OST4-tag

Specifically, the gut microbiota acts as a metabolic bridge: it ferment dietary nutrients to produce bioactive metabolites (e.g., SCFAs, tryptophan derivatives), which signal to the brain via three pathways: 1

ALA acts as a cofactor for pyruvate dehydrogenase and -keto-glutarate dehydrogenase activity (Schmidt et al., 1994), and is also required for the oxidative decarboxylation of pyruvate to acetyl-CoA, a critical step bridging glycolysis and the citric acid cycle (Reed, 1998)