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Ongoing clinical research is required to clarify long-term effects, optimal dosing, and durability of responses

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Figure 2 provides a summary of the mechanisms that may explain the anti-amyloidogenic effects of melatonin

38 In individuals with prominent dehydration (eg, athletes, malnourished individuals, or members of vulnerable populations), care must be taken to ensure adequate electrolyte-rich solutions, particularly high-salt formulations