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Prodrugs exhibit low toxicity in normal tissues and can be converted into highly toxic primitive forms in tumor tissues [5,6,7].This design allows prodrugs to be converted into active drugs by natural processes such as enzyme reactions, pH changes, or light exposure after they enter the body and reach a specific site

Gastroenterology 129 , 19371943 (2005)

used polyvinylpyrrolidone (PVP)-capped AgNPs (PVP-AgNPs) as matrices for MALDI MSI, enabling the simultaneous detection of lipids and other small metabolites from mouse brains, including compounds with low ionization efficiency, such as FAs and sterols

staggering by a few hours is also common to isolate any tolerability signal to one compound

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