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doi: 10.1002/ajmg.a.37144

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In a 2017 systematic review of 18 trials, including 1,143 subjects with rheumatoid arthritis, only 4 of 18 placebo-controlled trials showed a benefit of omega-3 PUFA supplementation (2.2-3.6 g/day for 12-36 weeks) on pain level reported by patients and/or assessed by physicians (158)

What we know Research studies investigating the impact of vitamin D supplementation in individuals with heart failure is at a very early stage In one randomized controlled trial, vitamin D supplementation (1,200 IU/day for 12 weeks) improved heart muscle performance in children with CHF