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Yes, Vitamin B12 injections are safe when administered by a trained healthcare professional

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In drug-induced pyridoxine deficiency, such as in patients taking isoniazid, a higher replacement dose is often used, for example, 100 mg IV or IM daily for 3 weeks, to rapidly correct the deficiency, followed by a maintenance dose of around 30 mg daily

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This typically manifests as a queasy feeling rather than actual vomiting

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