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Y.et al (2010)

Smith, S

These include findings published in journals such as Cell Metabolism, Nature Communications, Frontiers in Endocrinology, and others, which document MOTS-cs discovery, mechanisms of action, and potential benefits in various experimental models

In mice with CLP-induced sepsis, no relationship was identified of the loss of HS in glomeruli with small periglomerular arteriolar microvessel function and neutrophil endocytosis (96)

Amycretin offers the elegance of a single molecule activating both pathways, with the critical advantage of an oral formulation and phase 1b/2a data showing up to 24% weight loss at 36 weeks
