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doi: 10.3390/nu10070910
Martins et al 2007
OTUs were assigned using a closed-reference OTU picking approach, which referenced picks against SILVA (NR132) database [35, 36] by using UCLUST algorithm [37] with 97% of sequence identity
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The link between TMAO and MAFLD was first confirmed by a cross sectional observational study conducted by Chen and colleagues, they detected the plasm TMAO levels of healthy people and patients with MAFLD and found that the TMAO level of patients with MAFLD (0.434 M) is 4.17 times higher than that of healthy controls (0.104 M) (Younossi, 2019)
