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Biomedicines , 2021, 9: 361 Acknowledgements We thank the National Natural Science Foundation of China (22377053, 92153303, 22293051) and the Natural Science Foundation of Jiangsu Province (BK20202004)

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This peptide also appeared to modulate immune cell behavior, with reports of increased macrophage activity, which may support resolution rather than persistence of inflammation

Prevalence and Challenges Estimates suggest B12 deficiency affects a significant portion of the population (often cited around 610% or higher depending on criteria), with PA being a major non-dietary cause, especially in older adults

Mechanism of Action BPC-157 (Body Protection Compound) BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a protective protein found in human gastric juice