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Description
Multiple sclerosis (MS) is a chronic autoimmune disease affecting the central nervous system, characterized by demyelination and neurodegeneration

Therefore, the major oxidative burst during I/R occurs after the reexposure to oxygen during the so called warm ischemia time.7 Although the molecular mechanisms involved in I/R cellular responses are still not fully understood, a major role seems to be played by APE/Ref-1 and NF-B proteins in liver.42 Overexpression of APE/Ref-1 by adenoviral vector resulted in suppression of the reperfusion-generated oxidative stress in a mouse model.42 Liver transplantation (LT) is at present the only available choice for the treatment of end-stage hepatic disease

Selank and GABA receptor modulation Source: PMC4757669 Summary: This study investigated Selanks effects on GABA-A receptor binding and neurotransmitter systems in animal models, examining GABAergic pathway involvement.

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Cette forme est strictement rserve aux traitements spcifiques des symptmes de certaines pathologies chroniques
