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The solution was then filtered using Whatman Paper 1 (10 nm)

The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials

GSH stock buffer (consisting of EDTA (ehylenediaminetetraacetic acid, Sigma-Aldrich, Zwijndrecht, Netherlands), monosodium phosphate (Sigma-Aldrich, Zwijndrecht, Netherlands) and MilliQ) was added to supernatant to receive measurement sample

344 In a multicentre phase III clinical trial, 416 COVID-19 pneumonia patients were randomized to receive different doses of sarilumab (200 mg or 400 mg)