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Description
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At the molecular level, X-linked immune genes such as Tlr7 escape inactivation in females, promoting stronger antiviral responses, whereas age-related mosaic loss of the Y chromosome in males impairs leukocyte gene regulation

This dual inhibition results in greater DHT suppression, with some studies showing superior efficacy compared to finasteride

Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome