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GHK-Cu activates the TGF-/Smad signaling pathwaythe most potent endogenous stimulator of collagen productionwhile simultaneously enhancing production of connective tissue growth factor (CTGF) and FGF-2 that further amplify collagen expression

Here we found that fibrosis-induced ECM stiffening impaired alveolar epithelial cell compensation

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doi: 10.1016/j.molcel.2010.09.022 174 PennacchiettiSMichieliPGalluzzoMMazzoneMGiordanoSComoglioPM

The statistical calculations were done in the STATISTICA 8 software