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Today, 9 TRP channels (TRPA1, TRPC5, TRPM2, TRPM4, TRPM7, TRPV1, TRPV2, TRPV3, and TRPV4) are demonstrated to be activated by oxidative stress (Mori et al., 2016)

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For example, dopaminergic neurons in the SN pars compacta (SNpc) are highly susceptible to mitochondrial dysfunction and oxidative stress-induced apoptosis, while other regions like the striatum may engage distinct pathways (e.g., necroptosis or pyroptosis) influenced by glial cell interactions

17 In this paper, we present clinical, biochemical, ultrastructural, and molecular data for five new patients with the dermatosparaxis type of EDS

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