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Hydration is also known to reduce difficulties in the injection procedure

Wrist Extensor Tendonitis The tendons on the back of your wrist control finger extension and wrist movement

Blunted or impeded therapeutic response to vitamin B12 may be due to such conditions as infection, uremia, drugs having bone marrow suppressant properties such as chloramphenicol, and concurrent iron or folic acid deficiency

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Elderly patients with cardiac conditions or those taking loop or thiazide diuretics may be particularly vulnerable