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Description

The experimental values of the W parameter can be correlated by means of regression analysis by using regular polynomials as a function of 1 as follows: These empiric models can be used to estimate the drug solubility by means of back-calculation, resolving this property from the specific W value obtained in the respective polynomial regression (25, 26)

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Ghrelin is the endogenous ligand of the GH secretagogue receptor (GHS-R) 1a, another member of the seven-transmembrane receptor family G-protein coupled to the phospholipase C-phosphoinositide pathway (329,330)