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I cant say with certainty that vitamin B12 caused my acne, but I wish I had this information a year ago

TB-500 protocol considerations Reported dosing in the research literature: Starting dose: 500 mcg daily, subcutaneous injection Titration: Increase by 100 to 150 mcg every two weeks as tolerated Target dose: 750 to 1000 mcg daily by weeks five through twelve Weekly total: Approximately 5 mg per week at full dose Cycle length: Eight to twelve weeks, with optional extension to sixteen weeks TB-500 is typically administered once daily via subcutaneous injection, with consistent timing and systematic site rotation

New England Journal of Medicine (2025) The REDEFINE 2 Phase 3 trial evaluated CagriSema in 1,206 adults with overweight or obesity and type 2 diabetes in a 68-week, double-blind, placebo-controlled design