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Overall, although open-skull imaging studies tend to artificially enhance basal spine turnover rates, the consensus is that in adulthood dendritic spines are largely long-term stable

Kitachev KV, Sazonov AB, Kozlov KL, Petrov KI, Sliusarev AS, Khavinson VK (2014)

Immunohistochemical localization of oestrogen receptors and progesterone receptors in the human ovary throughout the menstrual cycle

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GLUT4 upregulation depends on stable NAD+ levels, further supporting the core mechanism of nicotinamide metabolism and NAD+ elevation
