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doi: 10.3390/molecules28010029 48 BayrHDixonSJTyurinaYYKellumJAKaganVE

This scoping review was carried out in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews) guidelines

Moreover, supplementation with a higher dosage of NAC (18 g/d) had a considerable impact on decreasing E2 compared with lower doses (12 g/d) ( P = 0049)

Short intervention durations and absence of longterm followup make it difficult to assess sustained effects or safety

Disrupted ROS additionally impairs granulosa and theca cell activity, altering steroid hormone production and resulting in erratic cycles