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Furthermore, IL-6 may regulate metabolic reprogramming in chondrocytes, particularly affecting lipid and amino acid metabolism, through activation of the JAK STAT pathway, thereby influencing the synthesis and balance of GSH and NADPH

For this purpose, antioxidant concentrations within the range used in cellular or biochemical applications were included in the assays

Quercetin supplementation does not alter antioxidant status in humans

doi: 10.4093/dmj.2019.0185
