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Moreover, FeS cluster assembly and disassembly in mammalian iron regulatory protein-1 (IRP1) alters the active site conformation and accessibility and determines whether IRP1 binds its mRNA targets in response to oxidative stress and intracellular iron levels (reviewed in Refs

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Plant Physiol 155:218 Foyer CH, Rowell J, Walker D (1983) Measurements of the ascorbate content of spinach leaf protoplasts and chloroplasts during illumination

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Thus, newborn Keap1 -knockout mice (in which Nrf2 is constitutively overexpressed) die from hyperplastic keratinization of the oesophagus and forestomach, which obstructively limits intake of food

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