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Inhibition of intracellular triglyceride lipolysis suppresses cold-induced brown adipose tissue metabolism and increases shivering in humans

Opiates such as morphine reliably inhibit the behavioral, electrophysiological and biochemical responses evoked by acute thermal, mechanical and other noxious stimuli in rats

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15 Although leucovorin rescue is a universal recommendation after HD-MTX administration, a retrospective single-center study conducted by Barreto and colleagues found no utility in empirically escalating doses in subsequent HD-MTX cycles after a patient had previously demonstrated delayed elimination