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Description
When NF-kB is activated in immune cells, it translocates to the nucleus and switches on the transcription of inflammatory genes

[135] Propionibacterium , the other commonly used bacteria, produce no exotoxins or endotoxins and are generally recognized as safe (have been granted GRAS status) by the Food and Drug Administration of the United States

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It explains why anti-inflammatory treatments like topical steroids provide relief, and why newer treatments targeting specific immune pathways show promise

Both are easy enough to do and get easier with practice
