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W., & Ames, B

Acetaminophen causes its harmful effects on the liver mainly through N-acetyl-p-benzoquinoneimine, an extremely toxic metabolite formed by cytochrome CYP 2E1 and CYP 1A2 enzymes

This process further activates inflammatory pathways and induces mitochondrial dysfunction

2.3 Construction of mouse infection model Fifteen C57BL/6 J mice were randomly divided into 3 groups, with 5 mice in each group

Aspirin blocks COX, antihistamines block histamine receptors, and so on
