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Description
Dkk2 inhibits Wnt signaling by binding to both the Wnt co-receptor Lrp5/6 and the transmembrane receptor Krm1/2, which results in internalization of Lrp5/6 and consequently reduction in the ability of the cell to respond to Wnt ligands 39
Alterations in glucocorticoid negative feedback following maternal Pb, prenatal stress and the combination: a potential biological unifying mechanism for their corresponding disease profiles
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It consists of 15 amino acids and has been extensively studied in preclinical research for its regenerative properties
doi: 10.1016/j.euroneuro.2020.07.004
