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The metabolites associated with glycolysis, tricarboxylic acid cycle (TCA cycle), and urea cycle, as well as amino acids and coenzymes did not exhibit clear changes indicating activated metabolic pathways (Fig

All four groups of mice underwent most of the hepatectomy (24 h water fasting before surgery), and samples were taken after 0, 1, 3, and 7 days of postoperative anesthesia (intraperitoneal injection of 1% pentobarbital sodium (7 L/g body weight), respectively (24 h water fasting before specimen collection)

P-TSH, Plasma Thyroid-Stimulating Hormone

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