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However, a recent study conducted by DeNicola discovered that the glutamate-cysteine ligase catalytic subunit (GCLC) can defend against ferroptosis induced by cysteine deprivation through facilitating the formation of -glutamyl-peptides, which can be enhanced by NRF2 [66]

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1998), but not in rat enterocytes (Coloso and Stipanuk 1989) or rat renal cortical tubules (Stipanuk et al

Based on currently available evidence, these concerns remain largely unanswered, which is why individualized medical evaluation remains important before beginning treatment. Dr