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(3) It induces electrophilic stress to inhibit IB translation that regulates secondary transcription via upregulated ATF3 but not Nrf-2, described as the IBATF3 inflammatory axis [210]
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Sirt1, Sirt6 and Sirt7 are predominantly localised in the nucleus, while Sirt2 is found in the cytoplasm, and Sirt3, Sirt4 and Sirt5 are found in the mitochondria (Yu et al., 2022)
Single cell proteomics analysis of drug response shows its potential as a drug discovery platform
