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Usage suggestions Dosage: It is recommended to start with 200-500 micrograms per day, taken orally in divided doses, for a course of 4-8 weeks

*Correspondence: Ritsuko Shimizu, [email protected] Specialty section: This article was submitted to Hematology Oncology, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

In vitro , maclurin significantly attenuated UVB induced ROS production, inhibited hydrogen peroxide induced reduction of melanin and decreased cell survival (Hwang et al., 2019)

However, it was observed that the activity of the hydrolysates of sarcoplasmic protein and myofibrillar protein were higher than that of GSH (IC 50 = 7.98mg/mL)

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