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Other classical NRF2 target genes mRNA expression were also investigated by RT-PCR: Heme Oxygenase 1 (HO1) and NAD(P)H Quinone Dehydrogenase 1 (NQO1), and enzymes related to glutathione utilization, such as the Glutathione Peroxidases 1, 2 and 3 (GPx1, GPx2 and GPx3), with all of them having reduced expression in the NCI H23 compared to A549 cells (Supplementary Fig

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How Vitamin B12 Affects Brain Chemistry and Stress Systems Neurotransmitter production B12, together with folate and B6, is essential for the methylation reactions that produce serotonin, dopamine, norepinephrine, and GABA the neurotransmitters most directly involved in regulating mood, motivation, calm, and emotional stability

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