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Indomethacin Indomethacin, an NSAID that participates in both innate and adaptive immunity [131], has been shown to reduce the proportion of M.tb antigen-triggered Tregs, reactions of M.tb specific cytokines, and proliferation of T cells in active TB
To withstand the potential cytotoxic effects brought by this unexceptionally high level of ROS, cancer cells are capable to regulate ROS levels by modulating the cellular antioxidant production, which allows them to adapt to oxidative stress and thus ensures their sustainable propagation [2]
