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Keywords: BPC 157, cytoprotection, hippocampus, ischemia, ischemia injuries, nitric oxide, peptide, reperfusion Pentadecapeptide BPC 157 is a novel mediator of Roberts cytoprotection and has bidirectional effects on the gutbrain axis

This compound proves to be a dualtarget XONLRP3 inhibitor, which can reduce uric acid and relieve inflammation, and could be an interesting and possibly promising approach for the treatment of gout [69]

Illustratively, BPC 157 counteracted lidocaine convulsions [60], and thereby, likely also lidocaines effects on the central nervous system (i.e., inhibiting nicotinic acetylcholine receptors, inhibiting presynaptic calcium channels in the dorsal root ganglion, inhibiting opioid receptors, inhibiting of neurite growth, inhibiting muscarinic cholinergic receptors, and preventing substance P from binding to natural killer (NK) cell receptors) [278,281,282,283]
Food contamination as a public health issue is primarily a matter for governments to resolve