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A strong protection, noted followingintragastric or intraperitoneal administration of BPC157, was fully abolished by coadministration ofphentolamine, clonidine, and haloperidol, andconsistently not affected by prazosin, yohimbine, ordomperidone

Finally, multiple treatments of BD show anti-ferroptosis action in different contexts

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In prostate cancer, for instance, rhamnetin induces apoptosis by modulating the Bax/Bcl-2 ratio, leading to mitochondrial membrane permeabilization, cytochrome c release, and caspase activation

doi: 10.1074/jbc.M115.692798