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Indeed, it has been demonstrated in experimental animal models, the deficiency of Cu could lead to hypertrophic cardiomyopathy

Riechers DE, Irzyk GP, Jones SS, Fuerst EP 1997 Partial characterization of glutathione S-transferases from wheat (Triticum spp.) and purification of a safener-induced glutathione S-transferase from Triticum tauschii
While this can significantly shorten the time required for the drug to take effect, it simultaneously alters the safety profile

While treatments like retinoids and chemical peels have their place, they often come with potential side effects, including redness, peeling, and sun sensitivity

Thrombocytopenia is frequently present
