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10.1161/circresaha.115.306301 57 GorriniC.HarrisI

Safety, tolerability, and pharmacokinetics of PL 14736, a novel agent for treatment of ulcerative colitis, in healthy male volunteers

252 Streptomyces hosts have a rich history of use in expressing natural product BGCs, with examples ranging across polyketides, NRPs, and others (Figure 23)

Jenkins, R

As pues, es aconsejable no slo estudiar compuestos en busca de su potencial nefrotxico, sino incorporar a los protocolos experimentales estudios mecanicistas sobre la toxicidad para clulas diana
