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Complement 5 inhibition ameliorates hepatic ischemia/reperfusion injury in mice, dominantly via the C5a-mediated cascade

The pathogenesis involves both innate and adaptive immune responses targeting bile duct cells and various extrahepatic tissues [241,242,243]
Lafleur, J
Gut-first parkinsons disease is encoded by gut dysbiome

Whether amino acid stimulation of the developing immune cells could modulate the CNS innate immune system via immune-microglia interactions should be further studied
