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(2) 62 nAChR activation in SH-SY5Y cells promotes neurite outgrowth via ERK/CREB phosphorylation, which increases evidence of the neuroprotection of nicotine ( However, it is critical to acknowledge that most preclinical evidence supporting nicotines therapeutic potential originates from acute toxin-based models (e.g., MPTP or 6-OHDA-induced neurodegeneration in rodents/non-human primates)
The prevalence of thyroid nodules with a diameter of more than 0.5 cm in Chinese adults is as high as 20.43% (15)
