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When the active, reduced form of glutathione (GSH) encounters a reactive oxygen species (ROS)such as a superoxide anion or a hydroxyl radicalit donates a reducing equivalent (an electron or hydrogen atom) to neutralize the threat

Antimelanogenic activity of hydrocoumarins in cultured normal human melanocytes by stimulating intracellular glutathione synthesis

However, adding glutathione dramatically extended the time Vitamin C remained stable

The druglike and orally bioavailable compounds identified herein are active in animal models of schistosomiasis with a broader range of developmental stages targeted than the drug of choice, PZQ