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Description

To preserve its functionality, Hb (which is also the most abundant cytoplasmic protein in RBCs) has to be maintained in the reduced state

genes related to antioxidant metabolism, which include MRP1 (material requirements planning), GCLC (glutamate-cysteine ligase catalytic subunit), HMOX1 (Heme oxygenase-1), KEAP1 (kelch-like ECH associated protein1), NQO1 (NADPH quinone oxidoreductase1), NRF2 (nuclear factor erythroid 2-related factor 2), SLC7A11 (solute carrier family 7 member 11), G6PD (glucose-6-phosphatedehydrogenase), GLS2 (glutaminase 2), GOT1(glutamic-oxaloacetic transaminase 1), SLC1A5 (solute carrier family 1 member 5) ( The expression levels of the ferroptosis-related lncRNAs PVT1 and GLUT3 are upregulated in GBM, and their expression levels are significantly positively correlated

Low molecular weight antioxidants terminate radical chain reactions

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