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These chemical scaffolds frequently yield screening hits due to nonspecific interfering mechanisms such as redox cycling that can generate reactive oxygen species or covalent adducts and metal chelation that can disrupt metalloenzyme function, leading to false-positive results across diverse assay formats (Xie et al., 2011)

Selenium: This trace mineral is a required component for the enzymes that allow glutathione to function properly

S1 displays the assessment of the risk of bias of our included studies

For best results, the drip is done once a week for 10 weeks, followed by maintenance sessions every 2-4 weeks