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Two doses of edaravone were selected to evaluate if the anti-oxidant exert a dose-dependent effect

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LuPone expressed frustration with audience members who disrupt performances with their phones, stating, "We work hard on stage to create a world that is being totally destroyed by a few, rude, self-absorbed and inconsiderate audience members who are controlled by their phones." [96] In October 2015, LuPone, along with the current Fantine on the West End, joined her castmates to celebrate the 30th anniversary of Les Misrables