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In clinical studies, TAMs are associated with poor prognosis, while the use of anti-inflammatory agents is associated with reduced instances of certain cancers
10.1039/d2fo03470k 24 FajemiroyeJ
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The specific mechanism may be by activating VEGF-A / VEGFR1 -mediated AKT and p38/MAPK signaling pathways to upregulate downstream eNOS expression, which may increase the NO product synthesis thus promote angiogenesis of gastric mucosa, and also interact with ER stress
It indicated that PPAR hinders liver growth and hepatocyte proliferation by inhibiting the HGF/c-Met/ERK1/2 pathway
