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Hotchkiss RD (1948)

CDPI shows several advantages over the nebulized solution form, including shorter administration (1 min) and an enhanced portability (Conole and Keating, Fluoroquinolones Fluoroquinolones belong to the family of quinolones, a group of molecules that is widely used as antibiotic because of their large spectrum of bactericidal activity, excellent bioavailability, rapid cellular uptake (Drusano, 1999) and tolerance (Grillon et al., 2013)

doi: 10.1111/acel.12330

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144 Based on estimates, under physiological conditions, one-third of the HSA exists as disulfides mixed with cysteine, homocysteine, or glutathione (HSA-S-S-R), whereas the rest of the HSA is in a reduced form with a free thiol in the Cys-34 residue (HSA-SH)