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Enzymatic Discoloration of Melanin Discoloration of melanin is an alternative method for skin lightening

IV therapy and IM injections are not recommended for individuals who are pregnant, breastfeeding, or currently receiving dialysis or diagnosed with kidney disease

Pooled estimates were calculated with the random-effects model, considering that the patients came from different populations

Acknowledgements The author thanks current and former members of his laboratory, The Scripps Research Institute Department of Immunology and Microbial Science, and the following funding sources: US Department of Health & Human Services, National Institutes of Health (NIH) grants R37AI059714, R01AI128836 and R01AI073148