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Providing support for a causal link between a negative energy state and increased Parasutterella abundance, a rat model of obesity, which showed similar Parasutterella relative abundances in animals maintained on HFD and those maintained on normal chow but exhibited a treatment-induced increase in Parasutterella relative abundance, displayed a negative correlation between Parasutterella and body weight 82

What is NNMT?+ NNMT (nicotinamide N-methyltransferase) is an enzyme expressed in fat tissue

The shedding is usually temporary, with regrowth occurring once weight stabilizes

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Studies of HSL knockouts have provided important insights into the functional significance of HSL and into adipose metabolism in general