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Metabolite addback and inhibitor treatment experiments were performed in the media conditions listed with supplementation of the listed metabolite or drug with equal volumes of vehicle control unless otherwise specified

The improved specificity of Nile Red imaging using 2p-FLIM allows capturing the information on tissue-specific distribution, localization, and dynamics of different types of lipid-rich particles, and thus will be useful in addressing outstanding problems related to fat regulation and aging in the field ( While we have previously shown that BCARS can provide deeper characterization, Nile Red 2p-FLIM is more accessible since BCARS is not yet commercially available

2017;37:BSR20160244

In good agreement with the localization of OCTN2 in the brain, the administration of carnitine-derivatives may sustain neuroprotection (Pochini et al., 2019)

Real-world use of similar GLP-1 receptor agonists like liraglutide and semaglutide extends beyond 5 years in some patients