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It is also important to consider the activity of fasting and/or fasting-mimicking conditions on the metabolism and autophagy flux of immune cells, as both significantly influence the outcome of immune responses (60)

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and ultimately attenuating gut permeability and metabolic endotoxemia, thereby hindering proinflammatory signaling pathways (25, 31, 34, 35)

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This is the mechanism behind prion diseases (such as Creutzfeldt-Jakob disease), and it leads to aggregation of both the mutant and the wild-type molecules

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[DOI] [PubMed] [Google Scholar] 124.Morray JP, Geiduschek JM, Ramamoorthy C, Haberkern CM, Hackel A, Caplan RA, et al

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