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These typically develop first in the feet and hands, presenting as a stocking and glove distal distribution, with the longest axons displaying abnormalities first before spreading proximally as the symptoms progress (Seretny et al., 2014)

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In addition, this mouse model had no tail-suspension-induced dopamine release in the anterior cingulate cortex

In addition to dry eyes and dry mouth, Sjogrens can also cause joint pain and swelling, prolonged fatigue, and other symptoms