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The reported adverse reactions following parenteral administration of vitamin B12 include: Generalized: Anaphylaxis and death Cardiovascular: Pulmonary edema and congestive cardiac/heart failure during early treatment

Severe side effects are rare

Preliminary studies suggest that liposomes optimize absorption by protecting the GSH from oxidation

82 ShibataT.KokubuA.SaitoS.Narisawa-SaitoM.SasakiH.AoyagiK.et al (2011)

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